More than 14 million people in Yemen and 9.9 million in Egypt lack a sink or soap at home, putting them at greater risk of infection, UN says.
The 150-bed facility includes 10 intensive care beds and 10 ventilators and will be staffed by 150 health workers who have received training.
Many of the city's impoverished residents find themselves forced to break the rules of quarantine in search of daily sustenance.
The government has approved additional support for the health sector after the first case of coronavirus was recorded in Hadramaut.
The first coronavirus case has been reported in Hadramaut province, as the Houthis dismiss Arab coalition truce that aims to fight its spread.
For many who were already struggling, meagre incomes have vanished since a curfew was imposed on March 24th to stem the spread of the virus.
The suspension of pre-Easter services comes as the country increases its measures to contain the novel coronavirus pandemic.
The kingdom joins other countries in the region in harnessing technology to fight the virus, as Lebanon begins to repatriate its nationals.
Medical teams and personnel are exempted from the curfew, which bans the movement of people and vehicles in the southern province.
The interior ministry has announced a 24-hour curfew in Mecca and Medina until further notice, increasing an earlier restriction.